
What happens if you take Adderall and weed?
It’s a common question asked among people who have a prescription for Adderall but also enjoy consuming marijuana recreationally.
Commonly referred to as “Madderall” or “Weederall,” combining Adderall and weed can be an incredibly bad experience, even for frequent consumers.
It’s common knowledge that it’s not a good idea to mix stimulants with depressants, though some suggest that each drug counteracts the adverse effects of the others.
There are a few critical things to know before you even consider combining the two, as it can cause a heightened state of paranoia as well as euphoria that you hadn’t prepared yourself for.
In this guide, we’ll explore what exactly happens when you take Adderall and weed together.
What Is Adderall?
It’s essential to consider what Adderall is and how it affects your system to get a clear idea of the effects you can experience from one half of the combination.
Adderall is one of the many stimulants approved by the U.S. Food and Drug Association.
It is comprised of dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate, and amphetamine sulfate.
These four chemicals are known to be amphetamine salts that give your central nervous system the stimulation it needs to counteract symptoms of ADHD or ADD.
In 1996, the FDA determined that Adderall would be a sufficient medication to help treat narcolepsy and ADHD.
When taken, the medication will increase the levels of norepinephrine and dopamine to boost activity in the brain.
However, every patient has a particular prescription based on their brain chemistry.
When taken accordingly, you’ll find that it helps to reduce your likelihood of hyperactivity, fidgeting, as well as any lack of focus that is typically attributed to ADHD.
Taking Adderall Recreationally
Unfortunately, there are plenty of individuals who also take Adderall as a recreational medication.
This effect has led many to believe that it’s a pure “study drug.”
Still, unfortunately, as these individuals do not have their own prescriptions, Adderall doesn’t work appropriately in their bodies.
Some students may experience heightened levels of concentration, which allows them to cram for tests overnight, whereas others may experience the inability to concentrate at all.
One of the most significant detriments to taking any medication prescribed or unprescribed is that they typically have long-term effects to be prepared for.
As someone suffering from ADHD, the long-term effects might not be as prevalent compared to someone taking the pills without a prescription.
Abusing Adderall can lead to a substantial number of ailments, including:
- Constipation
- Diarrhea
- Dry mouth
- Nausea
- Nervousness
- Headaches
- Excessive weight loss
- Painful menstrual cramping
What Is Marijuana?
Now that you have a clear idea of Adderall and what it is designed to do, let’s discuss marijuana.
Today, there are plenty of strains of marijuana that have THC content well above 13%, which is more than it has ever been.
There is a giant debate about the advantages and disadvantages of the drug, as many suggest it has changed their life for the better, while others don’t appreciate the way it makes them feel.
Marijuana is available in an assortment of forms, whether it’s a dry flower that you smoke, a salve that you rub onto your body, a tincture that you consume, or an edible that you eat like a treat.
It is also said to offer numerous benefits to particular people, such as helping to reduce pain and discomfort from illnesses, and aiding with relaxing the mind and body.
Most often, you will find that people consume it recreationally, though many are prescribed the drug to help with body pain.
Using Marijuana Recreationally
It can be relatively simple to get a medical card to consume marijuana legally if your state doesn’t allow recreational use.
However, similar to any other medication, you will need a prescription from your doctor that suggests the appropriate strength and dosage for your condition.
By not adhering to these recommendations, you will be one of the millions of Americans who have or currently use marijuana recreationally.
Fortunately, there’s far less damage associated with smoking weed for fun compared to taking Adderall for fun.
Though, you will find that the euphoric effects of the drug will affect every user differently.
Some weed enthusiasts find that it gives them a relaxed and mellow feeling, whereas others experienced heightened paranoia, insomnia, and severe hallucinations.
Some of the long-term results of using marijuana recreationally include:
- Cardiovascular distress
- Rising blood pressure
- Paranoia
- Panic attacks
- Hallucination
- Inability to sleep
- Anxiety
The Dangers of Marijuana
There’s no doubt that Adderall can become addictive, especially in youth who use it to enhance their scholarly performance or for fun.
However, did you know that marijuana can also be equally as addictive when it comes to self-medicating?
Although many people vehemently disagree that marijuana is addictive, it truly is a habit-forming drug, and breaking those habits can be incredibly difficult.
If you are an individual who has always relied on marijuana to assist you with your appetite, for example, not smoking weed can cause signs of irritability and stress.
The more often you use cannabis, the more reliant your brain and body are on it, and if you were to stop your use, you’d go through several consequences.
Most people don’t have a marijuana addiction, as they enjoy it every once in a while in social situations, for example.
Then again, there are many who do show signs of dependency, especially if they cannot go an entire day without smoking or consuming cannabis.
The most dangerous part of weed is how it works with your brain chemistry to make you feel like you are entirely reliant on it.
Also, as it can be quite useful for numerous ailments, living a life without weed can cause discomfort and distress in many.
What’s the Purpose of Mixing Weed and Adderall?
You would be surprised at the sheer number of recreational and prescription drugs people combine with marijuana, and you might be wondering why.
The most straightforward explanation is that users are always looking for a different experience, and the idea of combining two drugs that are deemed safe separately seems like an exciting and fun way to have a new high.
You may also find that users will take two drugs at the same time to counteract the adverse effects of both.
Take Adderall and weed, for example.
Smoking pot can help to improve your appetite while on Adderall, and taking Adderall while smoking weed can assist with eliminating the fogginess you experience while high.
However, this isn’t guaranteed for every consumer; some people find that taking two drugs exacerbates the harmful effects of both.
A negative example would be that weed can increase the anxiety and possible paranoia from Adderall, which defeats the purpose of the medication.
You may also find that you’ll feel more confused and less focused as soon as you smoke after being on Adderall for an extended period.
However, most have noted that combining the two creates a far more exhilarating high than taking either separately.
There is relatively little clinical research that has gone into the effects of mixing Adderall and weed; however, a published study in the Journal of Substance Abuse Treatment may shed a little bit of light.
During the exploratory study, two groups of healthy adults were orally administered THC and methylphenidate (MPH), which is one of the many drugs administered for ADHD.
One group received placebos, while the other received genuine medication, and in the group receiving the medication, interesting results were found.
The adults on MPH and THC experienced heightened heart rates as well as blood pressure.
They also noted there was a decrease in cognitive function when given a continuous performance test as well as a sharp decline in reaction times.
Overall, the study showed that there are physiological effects that occur when mixing an ADHD medication and weed.
With that said, it would be interesting to see more clinical data on the subject, as some of the results were subjective.

What Happens If You Take Adderall and Weed?
As of right now, most of the evidence about taking Adderall and weed is subjective, and if you research the subject, you’ll have to take the word of users around the world.
420 Intel gathered information from users who take both drugs simultaneously to create a chart of the effects you might experience.
With that said, it is essential to remember that the experience will differ from person to person, so you should always prepare for the worst.
When you combine weed and Adderall, the most likely effects you will experience are:
1. Increased Physical Stimulation
Marijuana and Adderall can increase your heart rate on their own, so when they are taken together, you are bound to experience a heightened level of stimulation.
This point is especially true if you take both drugs in excess rather than in moderation.
For some, the increased physical stimulation can be exciting; on the other hand, for others, it could trigger panic attacks and anxiety attacks.
You will also want to think twice about combining the drugs if you have a preexisting heart condition, as too much stimulation can be deadly.
2. Changes in Anxiety
Some users reported that they experienced a significant decrease in anxiety because Adderall can help to work away from the negative aspects of weed.
However, others have experienced worsening anxiety due to the stimulant properties of Adderall.
It’s more likely that you’ll have uncomfortable sensations if you have previous experience with nervousness, anxiousness, or a diagnosed anxiety disorder.
3. Heightened Euphoric Feelings
By far, this is one of the most commonly discussed features of combining Adderall and weed, as most users suggest it creates a new euphoric feeling.
Considering both of the drugs increase your dopamine levels, taking them together can create a wholly alleviated feeling.
The main concern with the euphoria from Adderall is that, over time, it will decrease the total amount of dopamine you have in your brain.
The best way to combine the two drugs is to consume marijuana when you feel like you’re coming down from the Adderall.
You’ll notice the effects of the comedown will be far less significant, as your dopamine levels will be raised again by consuming pot.
4. Increased Likelihood of Long-Term Ailments
At this point, there has yet to be a lethal dose of marijuana found among users, but there are several long-term health risks you’ll be facing with excessive Adderall use.
You might have to deal with depression, severe mood swings, panic attacks, depression, and a lot of fatigue.
What makes these effects dangerous, aside from their consequences on your health, is that they can trigger you to take more of the drug.
For example, if a lack of Adderall is making you feel miserable, you’ll take more and more to achieve the same high you once had.
Unfortunately, as your body builds a tolerance, a high becomes less and less likely, so you’ll continue to use more.
Over time, this can lead to even more long-term risks and a heightened chance of overdosing.
5. Social Alertness
If you are someone who has suffered from social anxiety in the past, it might be tempting to consider mixing weed and Adderall because of its ability to heighten social responses.
When the effects of the two drugs work together rather than counteract, you’ll have a far more pronounced experience, which can encourage you to engage in social situations you typically wouldn’t.
Some users have also noted they were able to explore a more profound consciousness while taking both drugs at the same time, though this could be a more extraordinary experience.
6. Increased Marijuana Tolerance
An interesting effect of mixing the two drugs is that you might be able to consume more marijuana than ever before.
Although this shouldn’t be necessary for most recreational situations, people have noted their tolerance for marijuana sharply increased after taking Adderall.
There is very little scientific evidence that can help you to decide whether taking Adderall and weed at the same time is safe or not.
This point is especially true, as some users report that it gives them a bountiful high that they have never experienced before.
Then again, it’s always a better option to stick to what you know, rather than to try a new combination of drugs that could be potentially hazardous on your health.
Can Marijuana Replace Adderall?
Self-medicating has become quite the craze, especially with the legalization of marijuana in over 11 states.
Many have found that marijuana, similar to Adderall, can help to counteract the symptoms of ADHD, rather than just calm down the harmful effects of ADHD drugs.
This point means that weed could be an answer to your attention disorder, instead of an auxiliary drug that you take to lessen the comedown of your prescribed medication.
Similar to the research about marijuana and Adderall use, most of the information you’ll find about weed and ADHD isn’t clinically significant.
However, it could bring some very interesting things to light as more research is put into this area.
In 2016, researchers conducted a qualitative analysis of online forums that discussed using cannabis while having ADHD.
Within the analysis, they found that 25% of their analyzed posts discussed how cannabis is therapeutic for ADHD, compared to 8% of the posts that described it as being harmful.
2% of individuals found it had no effect on ADHD, and 5% agreed that it was both therapeutic and adverse.
A second study of 30 adults with ADHD, randomized groups were given a THC-based oral spray while others were given a placebo.
During the study, participants were required to take cognitive performance tests to note any changes in their hyperactivity.
By the conclusion of the study, some adults showed improvements in hyperactivity, cognitive inhibition, as well as higher scores on the tests.
However, after looking at the overall performance scores, there was little difference between the active and placebo groups, which means that the findings aren’t statistically relevant.
Hopefully, more studies like this one can be conducted into determining the positive and negative effects of combining weed and Adderall.
How to Stop a “Madderall” Addiction
When an individual finds a drug or multiple drugs that give them a positive experience, of course, they are going to be likely to take those drugs continually.
Unfortunately, when it comes to Adderall and weed, it becomes a highly addictive combination that can be difficult to kick.
As you will be taking two drugs, you will have what is known as a polysubstance addiction, which may require a medical intervention to eliminate.
If you have noticed that you have become increasingly reliant on marijuana and Adderall, it is highly recommended that you seek a reputable therapeutic program to assist you with obtaining sobriety and maintaining it.
Simply because there are numerous long-term health effects you don’t want to experience due to drugs, getting help sooner rather than later is your best choice.
Talking to your doctor or any other medical professional will help you to find the proper course of treatment so that you can be guided through the detoxification process.
Final Thoughts
There are numerous effects you may or may not experience when dealing with a polysubstance addiction.
If you’re wondering what happens if you take Adderall and weed, the answers are likely subjective, as everyone’s body chemistry is different.
Overall, it appears that the combination of the two medications can lead to long-term health detriments, as well as a massive addiction that can be difficult to overcome.
You are far better off sticking to the prescriptions given to you by your doctor to appropriately treat the physical or mental disorders you are facing.
This really answered my problem, thank you!